What is the cheapest way of transportation from Serenade hotel to Altagracia on a Saturday evening or Sunday morning
Guagua from Friusa bus station.
From Cabeza del Toro, the bus can take you to an area we know as Coco Loco. It is an intersection across from San Juan shopping center. The bus to Higuey stops there every 30 minutes. There will be a person there to offer you guidance as to which bus to board. Try for the express bus. Once in Higuey, the bus stops right in front of the basilica.
Coming back is a totally different route.
The bus station is located about 1 mile away. You will have to ask someone for a ride. Taxis are always available.