Whether rocking out to music legends inside the Rock and Roll Hall of Fame or viewing Monets and Picassos at the Cleveland Museum of Art, Cleveland is a city that mixes equal parts grit and sophistication. Nosh award-winning food in historic buildings, tip back some craft beers amid a Lake Erie beach party or cheer on a championship team with a hardball of locally distilled spirits. All in Cleveland.

The history of St. Louis has been heavily influenced by Westward expansion and blues music. The big "must-see" in this region is the Gateway Arch, while other important sites include the Museum of Westward Expansion, the St. Louis Cathedral and the Anheuser-Busch factory tour. The city offers plenty for the whole family. Children will enjoy the local zoo and the Magic House, while family members will also want to unwind at Forest Park, home to the World's Fair almost a century ago.

About an hour south of Los Angeles, Laguna Beach has a spectacular clifftop setting above some of the finest beaches in California. Outdoor enthusiasts can snorkel, scuba dive, body-surf, or hike the trails in nearby Laguna Coast Wilderness Park. A center for artists, there are a number of special events and festivals,such as the Sawdust Art Festival, Festival of Arts/Pageant of the Masters, Art-A-Fair and Plein Air Painting Invitational. The Laguna Art Museum focuses on California artists. Window shoppers and collectors will enjoy strolling the village’s quaint streets, as well as visiting galleries spotted along Pacific Coast Highway.

Victoria is a thriving city of heritage architecture and time-honored traditions like afternoon tea. With the ocean at its doorstep and wilderness in its backyard, it’s also a perfect place for outdoor enthusiasts. You can find everything from a world-class science and natural history museum to a blooming public park where peacocks roam freely, plus a range of unique shops, cafes and restaurants. And more cycling routes than any other Canadian city, providing a great way to explore the scenery.

Every neighborhood in San Francisco has its own personality, from the hippie chic of the Upper Haight to the hipster grit of the Mission. The Marina district boasts trendy bistros and postcard-perfect views of the Golden Gate Bridge, while Noe Valley offers quaint and quiet boutiques. Wave hello to the sea lions at Pier 39, and sample local cheese and charcuterie at the Ferry Building. Sit in on a yoga session in Dolores Park or marvel at the Dutch Windmill across from Ocean Beach.

A gem of a city easily reached by rail from Liverpool. Small yet packed to the rafters with history, culture and stylish cafe/bar culture. At its heart, the historic black-and-white timbered "rows" provide a shopping experience like no other place on the planet.