Once a destination for honeymoons and family vacations, Niagara Falls has really stepped it up as an action-packed vacation spot. The falls are literally the biggest draw – watching the frothy water tumble at alarming speeds can be mesmerizing. Throw on a poncho and hop aboard the Maid of the Mist to cruise close enough to the falls to be drenched by spray. Hit the main strip of Clifton Hill for flashy tourist attractions and restaurants galore.

A popular spot for getting wowed or soaked amid natural splendor, Niagara Falls attracts curious spectators and adventurous honeymooners from around the world. The splendid main attraction - more than six million feet of water cascading over a rocky crest - sits partially in the United States and partially in Canada. The U.S. side has recently been busy promoting other activities to lure visitors. Venues like the Aquarium of Niagara offer parents fun and engaging alternatives for kids, after or in between visits to the Falls. Outdoor recreation such as hiking, biking, fishing and camping can be found at the Niagara Falls State Park. The storied history of attempts to conquer the majestic Falls is captured at the Daredevil Museum; the Schoellkopf Museum concentrates on the history and geology. There's more to the Falls than, well, the Falls, including a wide array of dining and lodging options, from budget to upscale. This awe-inspiring region makes for an exhilarating and multi-faceted getaway

Buffalo is being reborn as a mecca for art, architecture, history, culture, dining and entertainment. Experience Frank Lloyd Wright’s stunning Darwin Martin House Complex and world-class modern art at the Albright-Knox Art Gallery. Relive part of the city’s incredible history at the Theodore Roosevelt Inaugural National Historic Site. Explore the emerging Canalside waterfront district, hip Elmwood Village, more than 400 independently owned restaurants (serving our famous chicken wings and more) and nearby Niagara Falls.

The 150-year-old University of Notre Dame is South Bend's biggest tourist draw, and for good reason. Though it's not easy to land seats at the 80,000-plus-capacity Notre Dame Stadium for a "Fighting Irish" football game, you'll find plenty of attractions on the beautiful, expansive campus. Highlights include numerous works of art, the Basilica of the Sacred Heart and the Grotto of Our Lady of Lourdes, a replica of the famous shrine. Football fans will also want to visit the College Football Hall of Fame, which features interesting perspectives on the game and inductee videos. Whether or not you remember the Studebaker automobile, which saw its demise in the early sixties, you're sure to enjoy the Studebaker National Museum, featuring more than 75 vehicles drawn from the history of the company, beginning with horse-drawn carriages. South Bend has several fine museums, including the South Bend Regional Museum of Art and the Northern Indiana Center for History, a complex of four museums. Don't leave without trying truffles or fudge from the South Bend Chocolate Company.

The Texas Rangers and Dallas Cowboys both make their home in Arlington. Midway between Dallas and Fort Worth, the city has long been home to Rangers baseball and now also hosts the Cowboys. Their state-of-the-art structure is the world’s largest domed arena. Visitors looking for other adventures can enjoy the original Six Flags Over Texas and Hurricane Harbor water park, along with shopping, golf and nightlife. Arlington also has a vibrant culture of live music, symphony, museums and theater.

The Czech Republic's most famed spa destination, Karlovy Vary - or Carlsbad - saw 200 spa houses sprout by the end of the 1500s. The springs in this idyllic, lush, peaceful Tepla valley are said to cure an almanac's worth of metabolic and gastric issues. Visitors still flock to this town of Baroque and Art Nouveau buildings. Five beautiful Colonnades straddle hot springs where visitors try aquatherapy and drink the mineral-rich water. The town also has a respected international film festival.

An elegant resort town on the southern edge of Lake Garda, Sirmione has attracted vacation-goers for centuries. 13th-century Scaligero Castle and the Roman ruins of the Grotte di Catullo are top of the list for most visitors, as is swimming in the lake’s crystal-clear waters.

Vibrant Salta is a mashup of old world architecture and modern fun—a truly sophisticated bohemia! Marvel at the intricate façade of the old town hall—a Salta focal point—as you stroll from museums to markets. Savor the vintages at local wineries or take a train to a tiny village that's perched "at the top of the clouds." Thrill seekers will love the adventure sports and archaeological explorations that await at nearby Cabra Corral Dam.