Oakland, in the hub of the Bay Area, is both historic and modern. Visitors will find a little bit of everything in this diverse metropolis, from the picturesque waterfront to expansive hills. Explore Oakland's growing arts, entertainment and food scene or enjoy recreational opportunities like hiking, sailing and biking. Root for one of the three professional sports teams or take a tour of a historic landmark. The city is easily accessible through Oakland International Airport, train, automobile, BART, bus and ferry.

The counter-culture, flower power center of the 60s, bohemian Berkeley has evolved into a culinary and cultural travel scene. Shift into low gear and people-watch along quirky Telegraph Avenue while checking out the bookstores and cafes. After strolling through the UC Berkeley campus, the Berkeley Rose Garden and the Downtown Arts District, head into the hills for an outdoor adventure in Tilden Park or cruise down to the waterfront park, where the San Francisco skyline sparkles across the bay.

Gold and silver may have been behind the hordes that flocked in the 1800s, but liquid gold - Chardonnays, Cabernet Sauvignons and Pinot Noirs - is behind the modern migration. This dream destination for wine lovers has an abundance of fine restaurants and inns. Horse posts have been replaced by bike racks, and pedal power is a great way to explore.

Welcome to bustling San Jose, where Silicon Valley meets Spanish history and modern edifices sit alongside meticulously restored 19th-century buildings. Such is the contrast of this city rich in tradition and, thanks to the tech industry, just plain rich. Five star-hotels and fine restaurants line the streets of the restored downtown area, and the cultural scene is thriving with museums, theater and art to rival any world-class hub. Don't miss the Tech Museum of Innovation, an exploration of Silicon Valley and its impact on the area. History buffs will relish the old mansions and can delve into the city's past at the History Museum of San Jose. Save time for a round of golf or the locals' other favorite pastime, sipping coffee and people-watching at a crowded cafe.

Vines, wines and the people who love them are central to the economy of Napa Valley. Other treats for taste buds are in store, too, in the form of local olive oils, tomatoes, cheeses and mustard. The other senses are catered for with a vibrant visual arts scene. Rent a car or book a taxi or limousine to get between sights safely. The Napa Valley Wine Train offers an unusual way to experience the views and vintages. A relaxing array of spas and mud baths and the Old Faithful geyser are attractions in Calistoga.

Beautiful Northern California has many fabulous destinations, and the town of Healdsburg in Sonoma County is at the top of the list. Small town charm, beautiful landscapes and outstanding weather are just a few of the trademark qualities that make Healdsburg so popular. Healdsburg combines five-star cuisine, rolling hills and world-acclaimed wine growing appellations for an experience you will never forget. If you love the vibrant outdoors and colorful festivals, you will love Healdsburg. In April, you can help harvest roses and distill them into fragrant rose oil and rosewater as part of the Classic Perfume Rose Harvest & Distillation Tours. An annual sea food dinner at the Healdsburg Fire Department is also in April. From February to June, enjoy the "Russian River Good Old Days" exhibit at the Healdsburg Museum. And on the first Friday of the month, Williamson Wines sponsors an Epicurean Dinner at the Dry Creek Kitchen at Hotel Healdsburg.

California's capital city is often overlooked by tourists seeking out better known destinations in other corners of the state. Look again: Sacramento offers a range of exciting, educational and historic attractions sure to entertain all. Families will want to check out the cheetahs, jaguars and crocodiles at the Zoo while political buffs should head to the state Capitol, which features a park and museum on California history, or the Governor's Mansion. Anyone with an interest in trains will enjoy the Railroad Museum's massive collection of antique locomotives. Everyone will enjoy the restaurants and shops of historic Old Sacramento on the city's lovely waterfront.

About an hour south of Los Angeles, Laguna Beach has a spectacular clifftop setting above some of the finest beaches in California. Outdoor enthusiasts can snorkel, scuba dive, body-surf, or hike the trails in nearby Laguna Coast Wilderness Park. A center for artists, there are a number of special events and festivals,such as the Sawdust Art Festival, Festival of Arts/Pageant of the Masters, Art-A-Fair and Plein Air Painting Invitational. The Laguna Art Museum focuses on California artists. Window shoppers and collectors will enjoy strolling the village’s quaint streets, as well as visiting galleries spotted along Pacific Coast Highway.

In Ensenada, only 80 miles south of San Diego, travelers can get a taste of Mexican food, culture and nightlife. Californians flock to this beautiful seaport town, one of the largest on the Baja peninsula, for rest, relaxation and excellent outdoor recreation activities. From surfing and sea kayaking to horseback riding and mountain biking, even the most discerning sportsperson will be impressed. Ensenada's nightlife is also a big draw. Papas and Beer and Hussong's Cantina serve up an on-going party atmosphere and lots of tequila, while nearby vineyards offer wine tasting in a more traditional and serene setting. Nature enthusiasts are wowed by the sight of gray whales and the underwater cave that randomly squirts water at onlookers. Whatever your interests, enchanting Ensenada will not disappoint.

Since the redevelopment of the Inner Harbor in the late 1970s, Baltimore has set the standard for urban renewal. While a good part of the city's action centers around the fun and festive Harbor area, where street entertainers, open-air concerts, fireworks and parades abound, the surrounding neighborhoods offer all sorts of interesting landmarks, unique shops and delicious restaurants. Wander around Fells Point, the oldest section of Baltimore, reminiscent of an old English village, complete with pubs and cobblestone streets. Take the kids to the aquarium and check out the imaginative creations at the American Visionary Art Museum. Or stop by the Babe Ruth Birthplace and Museum for an in-depth look at the Great Bambino's life. Baltimore is also renowned for its African-American heritage sites, plus festivals and cultural events that take place throughout the year. From historic places and harbor cruises to family friendly attractions and fabulous neighborhoods, Charm City is one of the top tourist destinations in the United States.

Queens is the most ethnically diverse area of its size on Earth, which means there's a little something for everyone. Chow down on Indian food, sit in on a traditional Irish pub music session, and dance the night away at a Puerto Rican nightclub, all of it located within a few subway stops. Queens is also the home of the Mets and the US Tennis Open, and the former home of the New York World's Fair, now Flushing Meadow-Corona Park, and Paramount Pictures, now the Museum of the Moving Image.

You can easily fill a week with activities in and around the mountain village of Boquete. Tours of every sort—jungle tours, coffee estate tours, hiking tours. Adventures for every age—ATVs, zip lines, white water rafting. Or just relax and let your traveling companions do all the adventuring. Boquete's good for taking it easy, too.