Lucerne is an ancient town with strikingly modern sensibilities. One of Europe’s oldest covered bridges serves as its centerpiece, and fresco-adorned historic houses line the streets, but it’s also home to the cutting-edge KKL, a concert hall and art gallery. Take the cableways up the Pilatus, Stanserhorn or Rigi mountains for breathtaking views, or see Lake Lucerne on a steamship cruise.

So many of Madrid’s buildings look like castles, you’ll think you’ve stumbled into a fairytale. Even City Hall is astounding, with its white pinnacles and neo-Gothic features. A self-guided architecture tour can begin by the great bear statue in the central Puerta del Sol. Wander by the fanciful Royal Palace before absorbing the natural beauty of Retiro Park, then visit one of the city’s many museums. You could happily cap off each day by nibbling on forkfuls of paella while sipping Spanish rioja.

The Luxor in Las Vegas is to the actual CITY of Luxor, Egypt, as marshmallow fluff is to fois gras. (We’re sure you knew that. We just enjoy analogies.) Sure, the hotel/casino in Vegas might have a beam of light visible from space, but we bet you'll find a hot-air balloon ride over the Valley of Kings much more illuminating. (Editor's note: Our list was compiled before political unrest prompted many countries to issue travel warnings for Egypt. If you're currently planning a trip to Egypt, please consider the risks and monitor your government's travel alerts.)

Diverse marine life and hundreds of Red Sea coral reef sites make Sharm El Sheikh a magnet for divers and eco-tourists. The tourist economy of this Sinai Peninsula city has grown quite rapidly over the last few decades, resulting in an upcrop of first-class resorts and posh nightlife. The waters of Ras Mohamed National Park are abundant with schools of fish and, oddly, toilets – thanks to the bathroom fixtures being transported by a cargo ship that sank during a 1981 storm.

Want to make your co-workers insanely jealous? Just casually drop "I’m vacationing in the Maldives this year" into conversation, preferably in the dead of winter. Or better yet, go there without mentioning it to anyone—then send them a "Wish you were here!" postcard.