Cody, named for its legendary founder, Buffalo Bill Cody, remains as full of Old West adventure as it was during the days when Bill himself roamed Wyoming. Serving as the Eastern gateway to Yellowstone National Park, Cody is just a few miles away from pristine wilderness where actual buffalo can still be seen. The town attracts tourists and cowboys alike with reenactments of famous shoot-outs, restored frontier buildings and with the Cody Stampede, which the town hosts every July 4.

Whether you’re a high roller or a low-key lounger, Las Vegas has something to suit your vacation taste. Sample fare from top chefs and cornucopian buffets, try your luck at one of the world’s premier casinos, or take in a spectacular show. Just wandering the Strip is enough to get your heart pumping. Once you’ve had enough of the razzle-dazzle, wave hello to the toothy sea life at the Mandalay Bay Shark Reef, hike Red Rock Canyon, or visit the Neon Museum, where old signs take on new life.

True to its name, Hot Springs, Arkansas, is renowned for its thermal springs. Hot Springs National Park, and its hiking trails and bathing facilities, is the region’s starring attraction, while the city’s art deco architecture is another big draw for day-trippers from Little Rock.

The windy city is a cornucopia of modern art, fine dining, cutting edge comedy, and die-hard sports fans. Snap a photo of your reflection in the silver Cloud Gate sculpture at Millennium Park before heading to Grant Park to get hit with the refreshing spray of Buckingham Fountain. There are dozens of museums and theater companies in Chicago, so a cultural experience is never hard to find. You’re sure to laugh your head off at the Second City Theater, the professional launch pad of many famous comedians.

Strolling, shopping, and sipping tequila along the Malecon boardwalk of Puerto Vallarta is the best way to kick off your vacation. Then hit the cobblestone streets of Old Vallarta to browse the flea market for handmade crafts. The calm, warm waters of the Bay of Banderas make for excellent diving, or you can just watch artists sculpt spectacular creations in the sand. The cluster of fine art galleries in El Centro are perfect spots to hit on a self-guided art tour.

Welcome to Bluegrass Country, the "Horse Capital of the World." But you don't have to be an avid racehorse fan to enjoy the natural beauty, culture and history that this exciting city has to offer. At the Raven Run Nature Sanctuary, for example, hiking trails wend their way through forests, meadows and gentle creeks, taking you past historic landmarks; there's even a nighttime guided walk for stargazing. The best place in the world for raising thoroughbred horses, Lexington has over 500 horse farms. The Kentucky Horse Park features films, horse shows and exhibits. Be sure to tour the American Saddle Horse Museum, dedicated to the native Kentucky breed, and watch races at the lovely Keeneland Race Course in season. Historic sites are plentiful here, including the Waveland State Historic Site, the childhood home of Mary Todd Lincoln and the Ashland estate of famed Kentucky statesman Henry Clay.

Set against the misty blue backdrop of the Great Smoky Mountains National Park, Pigeon Forge, Tennessee is a gateway to 500 thousand acres of Appalachian wilderness. If hiking over 800 miles of mountain trails and camping in dense ancient forests isn't your thing, head over to Dollywood for a different sort of fun. Founded by country queen, Dolly Parton, Dollywood combines rollercoasters, waterslides, and live bluegrass and gospel concerts, with a down home country fair.

Atlanta has been dubbed everything from the "capital of the new South" and "the next international city" to "the best place to do business." It's also a great place to visit. Fueled by the prosperity of local mega companies like Coca Cola and Holiday Inn, the prestige of hosting the 1996 Summer Olympic Games and the energy of young upwardly mobile types who have migrated to the city in droves - Atlanta is on fire. And this time it's a good thing. From world-class restaurants and a myriad of cultural attractions to a hip nightlife and sporting events galore, the city is cosmopolitan in every sense of the word. But Atlanta has also managed to maintain its historic character. Stop by the Atlanta History Center or visit the Martin Luther King Jr. Historical Site, a moving tribute to an American icon. Browse through the former home of famous author Margaret Mitchell or pop into the Jimmy Carter Library and Museum for details on the life and times of the former president and his family. Whether you choose modern urban endeavors or old southern pleasures, Atlanta will not disappoint.

With more surviving 18th century buildings than any other city in the United States, visiting Annapolis is like stepping back in time to the days when the city was a colonial seaport. Known as America’s Sailing Capital, the city is located on the shores of the Chesapeake Bay and is a paradise for water lovers, famous for its crab cakes, lighthouses, and 500 miles of gorgeous shoreline. Tour the campus of the US Naval Academy, or the Maryland State House, the oldest state capitol still in use.

Cartagena, a gorgeous fishing village on Colombia's Caribbean coast, has excellent beaches, a historic old town (that's entirely walkable) and beautiful colonial architecture. It's also one of the safest places in the country, so it's no wonder it's a popular port of call for cruise ships. Need a break from exploring the cobblestone streets? Stop at an outdoor cafe for excellent pastries and people-watching.