Halfway between San Francisco and L.A., San Luis Obispo can be a relaxing getaway or a buzz of activity. For serenity, pack a lunch and head to one of dozens of wineries or take a drive to the beach for a leisurely swim. For a dose of history, visit the heart of the city at the beautiful Mission San Luis Obispo de Tolosa. Kids will love the Children’s Museum or Skate Park. Be sure to stroll along the creek downtown, where there are breweries, wine bars, restaurants and shopping for all tastes.

Lounge in style on the white beaches of the California coast. Pismo Beach offers premium ocean views, a 1200-foot pier perfect for fishing, and choice surfing. If you've had enough of bumming on the beach, check out the shops on the boardwalk or at the Pismo Beach Premium Outlets. Golfers will find plenty of desirable courses, and nature lovers will enjoy horseback riding or riding an ATV through the scenic sand dunes.

Monterey offers a host of historic attractions from Cannery Row to the famed Monterey Aquarium. This incredible sliver of oceanfront offers an amazing bounty of things to do, with marine, floral and vine-fresh delights to savor. Monterey-Salinas Transit and Amtrak let you take your eyes off the road. Charming towns, world-class golf courses and idyllic inns lie at the hem of the glittering Pacific. Whether you're looking for calm or noisy beachside fun, the Monterey Peninsula has it in buckets.

A mixture of urban chic and outdoor adventures, Spokane has something for everyone. Taste food by James-Beard-nominated chefs at Sante or The Wandering Table. Listen to live music at The Bartlett or the symphony at the iconic Martin Woldson Theater at The Fox. Glide over the breathtaking Spokane Falls, situated right downtown, in the SkyRide, rated as one of the world’s best gondolas. Kids can feed the Garbage-Eating Goat or slide down the giant Radio Flyer Red Wagon in Riverfront Park.

If you’re into eating locally and supporting sustainable agriculture, go to Asheville—and eat, eat, eat. This town of less than 100,000 people has 17 farmers’ markets, and the local restaurant scene is all about taking advantage of the seasonal produce sold there. And don’t miss the area’s microbreweries.

North Carolina'’s coast and 300 miles of barrier island beaches are filled with lovely state parks, top restaurants and world-class golf courses. Cape Fear’'s beaches attract surfers. Wilmington’'s downtown contains fine antebellum homes and exciting shopping and dining. The wind-swept Outer Banks offer historic lighthouses, mysterious Roanoke Island and the Wright Brothers National Memorial. Cape Hatteras National Seashore offers hiking, biking and fishing. Ferry trips link islands with the mainland.

Relaxing and pristine Kauai (the Garden Island) is the least commercially developed of the Hawaiian islands. Waterfalls, scenic drives and more than 60 beaches dot the landscape. Some beaches have great snorkeling, others offer child-friendly tidal pools and some are perfect for all kinds of water sports. Dry-land activities include hiking the Kalalau Trail on the Na Pali coastline, taking a day trip to Waimea Canyon and experiencing life on a sugar plantation at Grove Farm Homestead Museum.

Old world and new collide in Apia, Samoa's harborside capital. Traditional Samoan houses and buildings stand side by side with 19th century colonial churches and official buildings as well as late 20th century multistory structures. The central clock tower is surrounded by shops and markets, as well as nightlife in various bars and nightclubs. Vaiala beach offers snorkeling opportunities. The final resting place of writer Robert Louis Stevenson, Apia still houses his former home, now a museum.