Surpassed only by Manila in size, the Philippines’ second city combines colonial architecture and mountainous surrounds with a burgeoning cultural and culinary scene. As the gateway to both Bohol and Cebu Island, Cebu City impresses with chic rooftop bars and intriguing museums.

Most travelers know Panay as the jumping-off point for the white-sand, turquoise-water beaches in Boracay. But if you’ve got a few extra days to explore, you’ll find a whole lot more to the Filipino island—from the rugged mountains and rivers of Antique to the history and architecture of Iloilo City. It’s also a food-lover’s dream: Dig into the best seafood in the country (some travelers say) at Baybay Beach or hop over to Guimaras Island to try some of the sweetest mangoes in the world.

The city of Makati is the financial centre of the Philippines and one of the major financial, commercial and economic hubs in Asia. It is one of the most populous metropolitan areas in the world, and provides an eclectic mix of holiday rentals - from luxurious homes to small holiday villas and rental condos on the outskirts of the city. Makati is well known for its highly cosmopolitan culture, and many expatriates live and work in the city. It is also a major cultural and entertainment hub in Metro Manila.

Metropolitan Manila encompasses six cities and 12 towns. Located on Manila Bay in the South China Sea, and bisected by the Pasig River, the capital of the Philippines is historic and modern, rich and poor. A popular sight is the walled area called Intramuros. The capital during Spanish colonization, Intramuros has retained old dungeons and gunpowder rooms but added art galleries and theaters. The city is filled with museums, shops, parks and churches, plus enough nightlife to last until dawn.

Home to nearly nine million and powering an economy that exceeds both Hong Kong's and Thailand's, Osaka packs quite a punch. The confident, stylish city is a shopping hub, with fabulous restaurants and nightlife. It's an ideal base for exploring the Kansai region; Kyoto's World Heritage Sites, Nara's temple and Koya-san's eerie graves are within 90 minutes by train. Top city attractions include the aquarium, Osaka Castle, Universal Studios Japan and the futuristic Floating Garden Observatory.

Seoul is the business and cultural hub of South Korea, where skyscrapers tower over Buddhist temples. Take it all in from the N Seoul Tower, built atop a peak in Namsan Park. The teahouses and shops of Insadong give you a taste of Korean flavor, which you can further experience with a visit to the grounds and museums of Gyeongbokgung. UNESCO World Heritage Site Changdeokgung Palace is a fine example of authentic ancient architecture.

Commerce keeps Nagoya’s downtown popping with life, but there’s more than just manufacturing to this industrial powerhouse. Nagoyans meet for plates of crisp-friend miso katsu; make weekend trips to nearby Shinto shrines; and count down the days to the city’s autumn Nagoya Festival.

Tradition collides with pop culture in Tokyo, where you can reverently wander ancient temples before rocking out at a karaoke bar. Wake up before the sun to catch the lively fish auction at the Toyosu Market, then refresh with a walk beneath the cherry blossom trees that line the Sumida River. Spend some time in the beautiful East Gardens of the Imperial Palace, then brush up on your Japanese history at the Edo-Tokyo Museum. Don’t forget to eat as much sushi, udon noodles, and wagashi (Japanese sweets) as your belly can handle.

Probably best known for its eponymous beer, Sapporo—the capital of Hokkaido, Japan’s northernmost island—has maintained the youthful and open atmosphere of the 1972 Olympic Winter Games, drawing international visitors for its annual Snow Festival and its world-famous ramen. Those seeking out the full diversity of Japanese cuisine will want to visit: a city with a ramen-inspired theme park is one that embraces and pampers foodies.