The largest city in Switzerland is a major contemporary art and shopping destination. Important artworks are displayed in the Kunsthaus and the Rietberg Museum, while those who consider shopping an art can hone their skills along Bahnhofstrasse and Niederdorf. Chagall's stained glass windows in the Fraumunster amaze and Zurich's 500 clubs and bars, including several in swimming pools, pulse with life 'til the early hours. This city on Lake Zurich has excellent public transit and a free bike rental system.

This Swiss winter wonderland is also a summer playground. Snow-frosted peaks tower above charming towns and villages like Interlaken. Its position, between lakes Thun and Brienz, makes a perfect base for cable car rides up Jungfrau, Mšnch and Eiger or for hikes from traditional village Grindelwald. Thun offers exciting summer diving and sailing. To the west, the glitzy resort town of Gstaad attracts Europe's wealthy. Jungfrau Railway boasts Europe's highest station. The region is accessible by bus or car.

A magnet for skiers and hikers, these dramatic peaks – including the iconic Matterhorn – range from 3,000 to 15,000 feet and spread across three-fifths of the country. Abundant glaciers, scenic valleys and gorgeous alpine lakes add to the region's visual appeal. The Glacier Express train travels the 7.5-hour route through the Swiss Alps from Zermatt to St. Moritz, passing through fairy-tale villages and over 291 bridges along the way.

This Italian-speaking region in Southern Switzerland is on the border with Italy. Bellinzona is the capital, and Lugano is the most important city in the canton, known for its beautiful waterfront, steep hillsides and gorgeous lake views. Castelgrande is a lovely medieval castle overlooking the city that has recently been restored. The Centovalli Railway is a scenic train that operates between Locarno, Switzerland and Domodossola, Italy, traveling through the breathtaking "Hundred Valleys." Lake Como is nearby, the home of People magazine’s “Sexiest Man Alive,” George Clooney.

Lying on picturesque Lake Constance (or Bodensee in German), Konstanz has been a city since the first century AD, later gaining prominence as a religious center and then as the site of the only bridge crossing the Rhine River. The Old Town is one of Konstanz’s main attractions and is home to the city’s famed cathedral, originally dating from the 7th century. Due to a border anomaly, Konstanz lies on Switzerland’s land mass, and the Swiss town of Kreuzlingen is just a short walk away.

One of the world’s fashion capitals, Milan offers endless opportunities for chic shopping. Hit the artsy neighborhood of Brera for leather goods and Via Monte Napoleone for exclusive, expensive boutiques. The enchanting mosaics and glass vaults of Galleria Vittorio Emanuele II make shoppers feel like they’re wandering inside a painting. Take break from your spree to gape at the iconic Duomo, then grab tickets to a performance at La Scala. Post-opera, the Navigli district pulses with late-night activity.

“Must love winter sports” could be the slogan of this town at the base of Northern Italy’s Dolomite Mountains. Skiing, snowboarding, tobogganing, and every other way of gliding across the snow is the favorite topics here, even when summer is in full tilt and Nordic walking and other high-altitude activities get added to the agenda. Two gondolas and a funicular on the edges of town whisk you up to the nearby ski resorts, which connect to a dozen or so more nearby. That’s literally hundreds of miles of easily accessible ski trails with one lift ticket. Back down in the valley, the après-ski atmosphere takes over the cobblestone streets.

Over the centuries, many cultures have added their mark to this prized piece of land. Today, you can experience those influences firsthand by exploring Istanbul’s mahalles (neighborhoods). From the holy sites of Sultanahmet and the 19th-century European elegance of Beyoğlu to the high fashion of Nişantaşı, the vibrant café society of Kadıköy and the football-loving streets of Beşiktaş, it’s easy to see why travelers say that Istanbul isn’t just one city, but many cities within one.

Approximately 60 miles east of Antalya lies Side, another once important port town in antiquity. Side has become a popular holiday destination all by itself, but is well worth a day trip from Antalya. The village offers picturesque, narrow streets and lovely gardens while the long, white beaches invite swimming. Imposing monuments of antiquity, such as the Roman bath and the columns of the Apollo temple by the sea, complete the picture of a perfect combination of modern-day vacation pleasure and the treasures of history.

Tribal Terenife still shows influence from the aboriginal Gaunches people. Visitors clamber to conquer Mount Teide (Spain’s tallest peak) and to stretch out on the sands of Los Gigantes. Squawk hello to the playful parrots of Loro Park, or brave the petrifying drive to beautiful Masca Valley. For a true taste of Terenife, sample fresh farmhouse cheese and local bananas. A piece of delicate calado canario lace makes a special souvenir.

Though Mumbai can feel chaotic and crowded, there are peaceful moments to be found here. Nibble a paper cone of bhelpuri while you stroll the sands of Chowpatty Beach. Then, take a short walk to Mani Bhavan, where Mahatma Gandhi once lived, strategized, and was ultimately arrested. The markets are spirited places to bargain for spices or souvenirs. Take a guided tour of Dharavi – made famous by "Slumdog Millionaire" – for an eye-opening glimpse into what Mumbai life is like for nearly a million people.

The sandy coast of Goa is perfect for reclining by the sea. Nestle into a cushioned chair at a beach shack and savor a curry while you sip a Kingfisher beer, watching the sun slip lazily below the horizon. In Old Goa, the beautiful Basilica of Bom Jesus is a UNESCO World Heritage Site and a fine example of baroque architecture. Visit during Christmastime to experience a fantastic religious and cultural mash-up of East and West.

Mangroves meet sandy beaches in laid-back Maragogi, a growing town whose locals and visitors both head to the sea for sunset drinks and socializing. The most sought-after treasures are off the coast, where the Gales de Maragogi marine reserve shelters crystal-clear ponds, coral reefs, and colorful fish.

The Out Islands are synonymous with sport, from the depths of the Gulf Stream that yield big game fish to the coral reefs just off shore that are catnip to scuba divers. Sailing, kayaking and beach-combing add action to lazy days in the sun, while resident pink flamingos and rare Bahama parrots color local hikes.