Once infamous for dangerous gangs and drug activity, Medellin has been transformed. It’s now a vibrant destination for travelers seeking a culturally rich vacation. Medellin rises proudly from the belly of the Aburrá Valley, and its natural beauty makes a perfect setting for hiking, zip lining and horseback riding. Travel through lush jungle to Piedra de Penol, then climb the 740 steps to the top—a journey within a journey that rewards you with unforgettable views.

The City of Fernandina Beach is located on beautiful Amelia Island off the Atlantic coast of Florida. Play a round of golf on one of the champion golf courses, or take a tour of the historical sites on the island. Visit the Artrageous Artwalk. The galleries are opened from 5:30pm until 8:30pm the second Saturday of every month. Find pottery, stained glass, local crafts shown alongside fine art, watercolors, and intriguing photography.

Houston hums with an energy and independent spirit all its own. A leading cultural and culinary destination in the South, the city is home to over 11,000 restaurants featuring cuisine from more than 70 countries. The thriving arts scene includes resident opera, ballet, symphony and theater companies. The Museum District houses 19 museums, all within walking distance. Be sure to visit Space Center Houston, where you can visit NASA’s Historic Mission Control at the Johnson Space Center.

True to its name, Hot Springs, Arkansas, is renowned for its thermal springs. Hot Springs National Park, and its hiking trails and bathing facilities, is the region’s starring attraction, while the city’s art deco architecture is another big draw for day-trippers from Little Rock.

Greensboro, North Carolina loves nightlife, shopping, and horses (8,000 buyers per year go to the Sharpe Family Horse Farm.)  Greensboro lives up to its name in the host of gardens, science centers, and arboretums. The Bog Garden features a living wetland ecosystem. History is also at home here with museums dedicated to the Revolutionary War, the Civil War, and the Civil Rights movement. After a day of sightseeing, visitors flock to the Four Seasons Town Center for dinner, shopping, and a movie. 

Discover an essential chapter of America's history in the cobblestone streets, river walks and monuments of Richmond. Originally a colonial settlement, Virginia's capital is now a thriving hub for culture, shopping and outdoor fun. Explore Civil War history at the American Civil War Museum, stroll along the canal downtown or test your nerve whitewater rafting on the James River. With lively neighborhoods and a vibrant restaurant scene, Richmond is perfect for a quick break or an extended getaway.

Hilly Cincinnati boasts a thriving arts scene, major league sports teams, a world-class zoo and aquarium and a revitalized riverfront with shopping, clubs and restaurants. Located on the Ohio River in southwestern Ohio, Cinci claims more than 4,000 restaurants, and more chili restaurants than any other city in the world. Adrenaline-junkies will want to visit the nearby Kentucky Speedway and Paramount's Kings Island, home of the tallest and fastest wooden roller coaster in the world.

Pennsylvania Dutch country is a fascinating destination to explore. Visitors will get a glimpse of farm life as it was in the early 1800s. Visit markets and farm stores for homemade shoofly pie and fresh produce, or shop for a handmade quilt. President James Buchanan's elegant home, Wheatland, is no less historic but contrasts sharply to the simpler Pennsylvania Dutch heritage sites in Lancaster. Consider a side trip to nearby Hershey, home of Hershey Park and the Hershey chocolate factory.

Located on the shores of Lake Michigan, Milwaukee is perhaps best known for its famous breweries and the Major League Brewers, but there's more to the city than beer and baseball. Milwaukee is rich in historical and cultural attractions, making it the perfect place for a weekend of exploring. Check out the newly expanded Milwaukee Art Museum or the Mitchell Park Horticultural Society, which hosts an annual show of the same flora and fauna seen in Georgia O'Keefe's paintings. Those interested in the city's history can visit the grand Pabst Mansion, former home of one of the city's famous beer barons, or the Milwaukee Public Museum, to see what life was like in Old Milwaukee. If the kids are along, don't miss the Milwaukee County Zoo or the Betty Brinn Children's Museum. Of course a trip to the "Genuine American City" would not be complete without a tour of the Miller Brewing Company and a Brewers game at Miller Park.