Ollantaytambo has some of the oldest continuously-occupied buildings in South America. Once a stronghold of Inca resistance to Spanish colonization, it's remarkably well-preserved. Many travelers visit Ollantaytambo because it's the beginning of the Inca Trail to Machu Picchu, but don't rush through—the ruins are fascinating.

It's no wonder Machu Picchu is Peru's most-visited site. Dating to the mid-1400s, it's a marvel of mortar-free limestone architecture perched on a high plateau deep in the Amazonian jungle. Get there via train from Cusco or, if you're not faint-hearted, make the trip on foot via a multi-day hiking trail—you'll travel through deep Andean gullies and enjoy stunning views.

Peru’s Aguas Calientes offers weary travelers the chance to soak in thermal baths and browse for artisan souvenirs before (or after) using the town as a gateway to Machu Picchu. Its remote location deep in the Urubamba Valley is accessible to tourists only by train.

A laid-back village in the heart of the Patagonia region, Villa La Angostura is the perfect escape for vacationers who love the alpine feel of misty mountain forests. Nibble on locally made artisan goodies while you breathe in the crisp Andes air. Ski bunnies and snowboarders will fall in love with Villa La Angostura in the winter—it's an absolute fairyland of perfect powder.

Isn’t it romantic? The Caribbean island of St. Croix is practically the backdrop of a Hollywood love story. White sand beaches and lush rainforests set the scene for tropical bliss. Take in the historic small town charm of Christiansted and Frederiksted, sip your way through a spirited tour of the Cruzan Rum Distillery or explore the ruins of a sugar plantation. And the diving…oh, the diving. Think shipwrecks, think vibrant ocean life, think endless underwater possibilities.

Today the capital city and cultural center of Iowa is revitalized. A versatile destination everyone will enjoy, Des Moines has an itinerary for almost every interest. Culture and art enthusiasts may want to roam through the Des Moines Art Center, spend the weekend museum-hopping or attend a Broadway-caliber performance at the Civic Center. Golfers can spend their time and energy teeing up at any of the area's fine championship courses. The Blank Park Zoo and the Iowa State Fairgrounds should be on the list for families. And gardeners will savor the fantastic blooms at the Botanical Center and the Better Homes and Gardens Test Garden. Mix it up a little and sample all this "big city with a small town heart" has to offer.

Costa Adeje, on the southern side of Tenerife in the Canary Islands, is home to many newly-developed hotels that draw chic European guests. You’ll find great shopping (in boutiques and markets) and upscale restaurants, as well as plenty of sunny weather.