Once a vital part of a mighty sea power, Positano is today a sophisticated resort on the central Amalfi Coast. Moorish-style architecture rises up steep slopes that gaze out on the Sirenuse Islands. Smart boutiques, selling fashions for visitors to display on Grand Beach, abound in the village. And it’s a great base for exploring the area—you can easily travel by boat to Capri, Ischia and the Grotta dello Smeraldo cave.

Lying in south central Turkey, the moonscaped region of Cappadocia, southeast of Ankara, is most famous for unique geological features called fairy chimneys. The large, cone-like formations were created over time by erosion of the relatively soft volcanic ash around them. Past cultures have dug into them to create dwellings, castles (like Uchisar) and even entire underground cities like Kaymakli and Derinkuyu, used as hiding places by early Christians. Nearby Kayseri is the gateway to the area.

Amman's layered history is reflected in its diverse people and its varied architecture. The city is home to a multidenominational and multicultural population. Even within the midst of the ultra-modern commercial center, there is evidence of its ancient roots, with colorful souks, Roman ruins, cultural museums and monuments painting a picture of the history of the region.

A city trapped in time, Havana captures the imagination like no other. Faded glamour meets careful colonial-era reconstruction with a backdrop of irresistible color. Walk El Malecón, the walkway bordering the ocean; visit Old Havana and the Catedral de San Cristóbal; and listen for salsa music, open-air bazaars and parties that last all night.

The delightful village of Watamu is an eco-tourist’s dream, lined with sandy white beaches and hotels dedicated to sustainable tourism. Watamu is a quick snorkel away from the Malindi Marine Reserve Park, and Turtle Beach is the ideal spot for a swim and a tanning session. The village proper features quaint Kenyan shopping stalls called dukas, where you can stock up with supplies. Make sure to visit the Gede Ruins, a mysterious and heavily overgrown 12th century Swahili village, and the beautifully fluttery Kipepeo Butterfly Project.

Venture into the unspoiled beauty of 7,000-foot Rocky Mountain vistas, marvel at the contrast of ancient native culture mixed with modern arts, feast on legendary cuisine and relax in rustic sophistication. A visit to Santa Fe, Travel & Leisure's #1 Cultural Getaway, feels a lot like a visit to Europe. The Spanish Colonial charm of this historic destination has been enchanting travelers for over 400 years. And Santa Fe shows no signs of slowing down.