Conquering New York in one visit is impossible. Instead, hit the must-sees – the Empire State Building, the Statue of Liberty, Central Park, the Metropolitan Museum of Art – and then explore off the beaten path with visits to The Cloisters or one of the city’s libraries. Indulge in the bohemian shops of the West Village or the fine dining of the Upper West Side. The bustling marketplace inside of Grand Central Station gives you a literal taste of the best the city has to offer.

From the Magic Kingdom to magical spa treatments, Orlando sparkles with the promise of adventure. Spend a day exploring the world-famous Disney theme parks or screaming your head off on a Universal Studios roller coaster. For a less adrenaline-pumping afternoon, enjoy the quiet natural beauty of the Harry P. Leu Gardens or enjoy a seaweed scrub at a luxury day spa. Savor fresh and local ingredients at one of Orlando’s James Beard-nominated restaurants.

Hollywood beckons to tourists who long for a brush with Tinseltown glamor. Tour movie studios, slip your hands into the famous prints at the TCL Chinese Theatre, or indulge in a celeb sighting at one of LA’s white-hot nightspots. Spot your favorite star while shopping at The Grove, or forget all about the famous eye candy as you take in the iconic artwork at The Getty Center. For a different type of star-gazing, peek through the telescopes at the Griffith Observatory.

Vancouver was founded as “Gastown” by an Englishman with a penchant for beer and storytelling. Today Gastown is a historic section of the Canadian metropolis, and the lively pubs still reflect the area’s former status as a sort of community drinking center. The city’s forests, grand parks, and impressive suspension bridge beckon travelers to explore them, as do the city’s shops and museums. Relive the glory of the 2010 Winter Games with visits to Olympic venues and the marvelous Olympic Cauldron.

Every neighborhood in San Francisco has its own personality, from the hippie chic of the Upper Haight to the hipster grit of the Mission. The Marina district boasts trendy bistros and postcard-perfect views of the Golden Gate Bridge, while Noe Valley offers quaint and quiet boutiques. Wave hello to the sea lions at Pier 39, and sample local cheese and charcuterie at the Ferry Building. Sit in on a yoga session in Dolores Park or marvel at the Dutch Windmill across from Ocean Beach.

From Shoreditch’s swaggering style to Camden’s punky vibe and chic Portobello Road, London is many worlds in one. The city’s energy means that no two days are the same. Explore royal or historic sites, tick off landmarks from your bucket list, eat and drink in exclusive Michelin-starred restaurants, enjoy a pint in a traditional pub, or get lost down winding cobbled streets and see what you stumble across – when it comes to London, the possibilities are endless.

Set in the heart of the Algarve, the tiny fishing town of Olhos de Agua surrounds a sandy cove lapped by the Atlantic Ocean. Despite its proximity to the developed Albufeira resort, Olhos de Agua retains its authentic Mediterranean charm.

So many of Madrid’s buildings look like castles, you’ll think you’ve stumbled into a fairytale. Even City Hall is astounding, with its white pinnacles and neo-Gothic features. A self-guided architecture tour can begin by the great bear statue in the central Puerta del Sol. Wander by the fanciful Royal Palace before absorbing the natural beauty of Retiro Park, then visit one of the city’s many museums. You could happily cap off each day by nibbling on forkfuls of paella while sipping Spanish rioja.

When most people think of Zermatt, they think of one thing: The Matterhorn. This ultimate Swiss icon looms over Zermatt, first drawing visitors here in the 1860s. The village of Zermatt itself is lovely and car-free, with old-fashioned brown chalets and winding alleys. (Don’t worry, you don’t have to walk everywhere—there are electric vehicles and horse-drawn cabs.) Skiing in the region often lasts through early summer, but when the weather’s warmer, it’s a great time to hike.

Munich exudes Bavarian charm. Beer fanatics should head immediately to the Hofbräuhaus, a hops heaven that’s been churning out the good stuff since 1589. The drinking is downright legendary during Oktoberfest, a celebration of local beers and German specialty foods. Emulate world-class athletes at the Olympiapark, where skating on the Olympic ice rink will make you feel like a champion. The promenade of Marienplatz is perfect for people watching and gawking at the Glockenspiele of City Hall.