Famed throughout Asia for its heady mix of eastern cultures, Penang Island is Malaysia’s prime melting pot. Roadside vendors serve some of the world’s best street food; its national parks offer white-sand beaches and wildlife; and UNESCO-listed George Town is full of colorful heritage houses.

Baguio, perched high in the Cordillera Central Mountains, is a great place to escape the heat of the Philippine lowlands. Camp John Hay, originally built as a recreation area for U.S. soldiers, now is a full-fledged resort complete with a world-class golf course. Definitely stop at the city market, where you can buy almost anything (just be prepared to haggle).

Bali is a living postcard, an Indonesian paradise that feels like a fantasy. Soak up the sun on a stretch of fine white sand, or commune with the tropical creatures as you dive along coral ridges or the colorful wreck of a WWII war ship. On shore, the lush jungle shelters stone temples and mischievous monkeys. The “artistic capital” of Ubud is the perfect place to see a cultural dance performance, take a batik or silver-smithing workshop, or invigorate your mind and body in a yoga class.

The largest city in China is also its most cosmopolitan, offering visitors a chance to experience the past, present, and future all at once. The Huangpu River splits Shanghai into two districts: Pudong and Puxi. The Pudong skyline looks like it was ripped from the Jetsons, with the bulbous Oriental Pearl TV and Radio Tower looking a bit like a two headed lollipop. On the Puxi side, you can walk the Bund riverside district to get a taste of old Shanghai.

Surpassed only by Manila in size, the Philippines’ second city combines colonial architecture and mountainous surrounds with a burgeoning cultural and culinary scene. As the gateway to both Bohol and Cebu Island, Cebu City impresses with chic rooftop bars and intriguing museums.

Once a vital part of a mighty sea power, Positano is today a sophisticated resort on the central Amalfi Coast. Moorish-style architecture rises up steep slopes that gaze out on the Sirenuse Islands. Smart boutiques, selling fashions for visitors to display on Grand Beach, abound in the village. And it’s a great base for exploring the area—you can easily travel by boat to Capri, Ischia and the Grotta dello Smeraldo cave.

An easy train stop in Emilia-Romagna, Ferrara shines with the former glory of its Renaissance past. A stroll or bike ride past remarkably intact castles and defensive walls makes it say to see how this northern Italian gem scored UNESCO World Heritage status.