From the Magic Kingdom to magical spa treatments, Orlando sparkles with the promise of adventure. Spend a day exploring the world-famous Disney theme parks or screaming your head off on a Universal Studios roller coaster. For a less adrenaline-pumping afternoon, enjoy the quiet natural beauty of the Harry P. Leu Gardens or enjoy a seaweed scrub at a luxury day spa. Savor fresh and local ingredients at one of Orlando’s James Beard-nominated restaurants.

Houston hums with an energy and independent spirit all its own. A leading cultural and culinary destination in the South, the city is home to over 11,000 restaurants featuring cuisine from more than 70 countries. The thriving arts scene includes resident opera, ballet, symphony and theater companies. The Museum District houses 19 museums, all within walking distance. Be sure to visit Space Center Houston, where you can visit NASA’s Historic Mission Control at the Johnson Space Center.

Welcome to Bluegrass Country, the "Horse Capital of the World." But you don't have to be an avid racehorse fan to enjoy the natural beauty, culture and history that this exciting city has to offer. At the Raven Run Nature Sanctuary, for example, hiking trails wend their way through forests, meadows and gentle creeks, taking you past historic landmarks; there's even a nighttime guided walk for stargazing. The best place in the world for raising thoroughbred horses, Lexington has over 500 horse farms. The Kentucky Horse Park features films, horse shows and exhibits. Be sure to tour the American Saddle Horse Museum, dedicated to the native Kentucky breed, and watch races at the lovely Keeneland Race Course in season. Historic sites are plentiful here, including the Waveland State Historic Site, the childhood home of Mary Todd Lincoln and the Ashland estate of famed Kentucky statesman Henry Clay.

Whether rocking out to music legends inside the Rock and Roll Hall of Fame or viewing Monets and Picassos at the Cleveland Museum of Art, Cleveland is a city that mixes equal parts grit and sophistication. Nosh award-winning food in historic buildings, tip back some craft beers amid a Lake Erie beach party or cheer on a championship team with a hardball of locally distilled spirits. All in Cleveland.

Conquering New York in one visit is impossible. Instead, hit the must-sees – the Empire State Building, the Statue of Liberty, Central Park, the Metropolitan Museum of Art – and then explore off the beaten path with visits to The Cloisters or one of the city’s libraries. Indulge in the bohemian shops of the West Village or the fine dining of the Upper West Side. The bustling marketplace inside of Grand Central Station gives you a literal taste of the best the city has to offer.

About an hour south of Los Angeles, Laguna Beach has a spectacular clifftop setting above some of the finest beaches in California. Outdoor enthusiasts can snorkel, scuba dive, body-surf, or hike the trails in nearby Laguna Coast Wilderness Park. A center for artists, there are a number of special events and festivals,such as the Sawdust Art Festival, Festival of Arts/Pageant of the Masters, Art-A-Fair and Plein Air Painting Invitational. The Laguna Art Museum focuses on California artists. Window shoppers and collectors will enjoy strolling the village’s quaint streets, as well as visiting galleries spotted along Pacific Coast Highway.

Hollywood beckons to tourists who long for a brush with Tinseltown glamor. Tour movie studios, slip your hands into the famous prints at the TCL Chinese Theatre, or indulge in a celeb sighting at one of LA’s white-hot nightspots. Spot your favorite star while shopping at The Grove, or forget all about the famous eye candy as you take in the iconic artwork at The Getty Center. For a different type of star-gazing, peek through the telescopes at the Griffith Observatory.

If you're into wine-tasting, a weekend in Santa Rosa is certain to be satisfying. But this region of magnificent redwoods, rolling hills and ocean vistas has a great mix of other fun pastimes as well. Located right in the center of the Sonoma County wine region, Santa Rosa is home to several vineyards with world-class wines, rich histories and beautiful surroundings. The Matanzas Creek Winery offers June and July visitors a chance to enjoy its aromatic fields of blooming lavender, but its Estate Gardens and spectacular scenery are tourist draws year-round. If golf is your passion, grab your clubs and spend a relaxing afternoon at Fountaingrove or one of the other popular courses. Young and old alike will delight in the Charles M. Schulz Museum, which chronicles the evolution and history of Snoopy and the "Peanuts" gang. With wine or without, a trip to Santa Rosa is one you'll never forget.

Santiago is one of those metropolitan joys where the more you look, the more you find. Funky cafes and dance clubs dot Bellavista, Forest Park art collections range from pre-Columbian to contemporary, and architecture runs the gamut from the 16th-century San Francisco Church to mirrored office towers. Shop with the locals at Mall Panora¡mico and give your palate meals to remember with hearty Chilean fare.