San Pedro is "La Isla Bonita" that Madonna made famous. Now it's a tourist mecca, but still boasts great beaches and plenty of dive shops so you can enjoy the sun, sand, and sea. Plan a side trip to Caye Caulker while you're here; it is less developed and more laid back, and has its own splendid swimming areas.

Ambergris Caye hovers in a vacation sweet spot: just enough amenities to make it exciting, but not so overdeveloped that you’re tripping over flip-flopped tourists. A mangrove swamp is the eye of this white beach island, the largest in Belize, and golf carts are the main form of transportation along the sandy roads. Reef divers drool over the Belize Barrier Reef and the Blue Hole, a 400-feet deep circle of limestone that teems with angelfish, elkhorn coral, cleaner shrimp and stalactites.

Located on the east coast of Belize at the mouth of the Belize River, Belize City sits on a peninsula jutting into the Caribbean Sea. As the nation's main port, the city is a hub for cruise ships and is often a jumping-off spot for excursions to other parts of Belize, including the Cayo District's caves and Maya archaeological sites along the Macal and Belize rivers. Belize City boasts the only manual swing bridge in the world and the oldest Anglican cathedral in Central America.

Located near the Mexico-Belize border, a true paradise awaits travelers in Bacalar. The town sits on the Lagoon of Seven Colors, a lake nicknamed for its beautifully colored water, which makes it the perfect place for stunning sunsets, fresh seafood, and cenote swimming.

It’s true: parts of Belize are getting touristy. But San Ignacio remains rustic, making it a great base for budget-friendly tropical adventure travel. Canoe on the Macal River, or walk to Mayan ruins at Cahal Pec (just be warned: it's uphill).

Once a sleepy fishing village, Placencia has emerged as an increasingly popular eco-destination on the Caribbean. For those who enjoy outdoor adventure, the Stann Creek region offers a host of activities: hiking through mountainous rain forests, kayaking, deep sea fishing, diving and exploring Mayan ruins. The peninsula boasts 16 miles of tranquil beaches, with a lagoon to the west and the Caribbean to the east and lots of peace and quiet in the middle. Tour guides and dive centers offer a variety of excursions, with boat rides to the outer cayes an ongoing favorite. Also popular are guided land tours to Mayan Ruins or trekking the jungle trails of Cockscomb Basin Wildlife Sanctuary, where the first Jaguar Reserve in the world was established.

"The Festival Capital of Louisiana," Lake Charles hosts over 75 festivals each year, the most famous being Mardi Gras, the second largest in the state. The annual celebration attracts revelers with Cajun cook-offs, a children's carnival and a lighted boat parade. The city celebrates its local heritage with "Louisiana Pirate Festival," a two week long party in honor of the pirates that once sailed the local lake. The Central School Arts & Humanities Center is a stop on the African American Heritage Trail.

Hilly Cincinnati boasts a thriving arts scene, major league sports teams, a world-class zoo and aquarium and a revitalized riverfront with shopping, clubs and restaurants. Located on the Ohio River in southwestern Ohio, Cinci claims more than 4,000 restaurants, and more chili restaurants than any other city in the world. Adrenaline-junkies will want to visit the nearby Kentucky Speedway and Paramount's Kings Island, home of the tallest and fastest wooden roller coaster in the world.