San Pedro is "La Isla Bonita" that Madonna made famous. Now it's a tourist mecca, but still boasts great beaches and plenty of dive shops so you can enjoy the sun, sand, and sea. Plan a side trip to Caye Caulker while you're here; it is less developed and more laid back, and has its own splendid swimming areas.

Ambergris Caye hovers in a vacation sweet spot: just enough amenities to make it exciting, but not so overdeveloped that you’re tripping over flip-flopped tourists. A mangrove swamp is the eye of this white beach island, the largest in Belize, and golf carts are the main form of transportation along the sandy roads. Reef divers drool over the Belize Barrier Reef and the Blue Hole, a 400-feet deep circle of limestone that teems with angelfish, elkhorn coral, cleaner shrimp and stalactites.

It’s true: parts of Belize are getting touristy. But San Ignacio remains rustic, making it a great base for budget-friendly tropical adventure travel. Canoe on the Macal River, or walk to Mayan ruins at Cahal Pec (just be warned: it's uphill).

Akumal means "Place of the Turtle" in the Mayan language, and if you snorkel here, you just might see one swimming alongside you. (Don’t touch it, though. That’s prohibited by law.) You’ll definitely see coral and beautiful fish in the clear, sparkling waters. This tourist-friendly little town is about an hour south of Cancun—but it seems light-years away.

Tamarindo is a prime spot for surfing and sportfishing, diving and sunning. Nesting leatherback turtles do their thing along the beaches from October to May and, for some nesting of your own, gorgeous beach houses, B&Bs and luxury hotels line the sunny sands. Shopping and dining options are superb and plentiful, perfect for sampling the true flavors of Costa Rica.

You can easily fill a week with activities in and around the mountain village of Boquete. Tours of every sort—jungle tours, coffee estate tours, hiking tours. Adventures for every age—ATVs, zip lines, white water rafting. Or just relax and let your traveling companions do all the adventuring. Boquete's good for taking it easy, too.

Rising from the ruins of the Aztec capital, Tenochtitlan, Mexico City offers a unique collision of contemporary city life and historic preservation. World-class museums, restaurants and parks rub shoulders with the remains of several cultures. The nightlife, the shopping and the history make it a must-see regardless of your travel style.

Normally, one wouldn’t equate "relaxing spa vacation" with "hanging out near an active volcano," but if you’re up for something more exotic than facials and massages, Banos might be the perfect place for you. The thermal mineral pools here are heated by the volcano, and while there are several, offering different amenities, the easiest one to visit is Las Piscinas de la Virgen. Banos also has plenty of outdoor activities, like rafting and biking on scenic paths.

Lima, founded by Francisco Pizarro in 1535, is a fascinating city and a treasure trove of history. Explore ancient Incan archeological sites, or stroll through the elegant cathedrals and opulent palaces dating from Spanish colonial times. Downtown Lima is crowded, but you'll enjoy exploring the city's neighborhoods—especially the beachfront areas, which have great shopping and dining and fabulous hotels.

Refer to Vancouver Island as Victoria Island and risk a chorus of eye-rolls from the otherwise-friendly locals. Yes, Victoria is the main city on the island, but there are many distinct flavors to its logging and fishing settlements. Food and wine enthusiasts flock to the Comox Valley farm region, while the more outdoorsy types get their fix along the remote, forested beaches of North Vancouver Island. Visit the UNESCO Biosphere Reserve at Clayoquot Sound and you’ll return full of cocktail-party factoids.

From Alberta’s southwestern border north into British Columbia, the Canadian Rockies are a network of provincial and national parks that collectively make up a UNESCO World Heritage Site. Banff and Jasper national parks are connected by the Icefields Parkway, one of the most scenic drives in the world. The towns of Canmore, Banff, Lake Louise and Jasper are hubs for adventures including hiking, horseback riding, rafting and wildlife viewing. Accommodation ranges from hotels to mountain lodges.

Giant anteaters, howler monkeys, ocelots, endangered jaguars and clouds of butterflies are among the attractions at this World Heritage-designated park that marks the border between Brazil and Argentina. By foot or by raft, explorers can view one of the world's most stunning waterfalls, Iguazu Falls. Among the park's 270 waterfalls, spectacular Devil's Throat combines 14 falls and generates a "perpetual rainbow" in good weather.