Conquering New York in one visit is impossible. Instead, hit the must-sees – the Empire State Building, the Statue of Liberty, Central Park, the Metropolitan Museum of Art – and then explore off the beaten path with visits to The Cloisters or one of the city’s libraries. Indulge in the bohemian shops of the West Village or the fine dining of the Upper West Side. The bustling marketplace inside of Grand Central Station gives you a literal taste of the best the city has to offer.

Queens is the most ethnically diverse area of its size on Earth, which means there's a little something for everyone. Chow down on Indian food, sit in on a traditional Irish pub music session, and dance the night away at a Puerto Rican nightclub, all of it located within a few subway stops. Queens is also the home of the Mets and the US Tennis Open, and the former home of the New York World's Fair, now Flushing Meadow-Corona Park, and Paramount Pictures, now the Museum of the Moving Image.

Newark has been welcoming guests since its first hotel opened in 1670. From the largest number of cherry blossoms in the U.S. to one of the country's highest grossing arenas, from Shaquille O'Neal's supersized cinema to the biggest collection of Tibetan art outside Southeast Asia, it's all still happening in Newark. Just eight miles from New York City, Newark offers travelers quick access and easy connections. Jump in and discover pro sports, fine arts, urban retail and outdoor adventure.

Any city that can be the butt of a Simpson's joke ("That's it! We're all going back to Winnipeg!") and simultaneously one of the most vibrant cultural centers in Canada is tops in our book. The city's history of isolation and self-sufficiency means that Winnipeggers are unpretentious and sincere (and fun-loving enough to name Homer an honorary citizen). Though the winters are long and cold, there are plenty of indoor activities to both keep you warm and stimulate your imagination.

The ideal destination for families, honeymooners, divers and golfers alike, La Romana is home to the famous Casa de Campo resort, internationally renowned golf courses, a world-class marina and Altos de Chavón, a beautiful replica of a 16th-century artisan village. Nearby, the Bayahibe area offers picturesque beaches, chic accommodations, desirable attractions and splendid opportunities for ecotourism. Visitors can enjoy stunning Saona Island, Cotubanamá National Park and more.

The festive city of San Juan is the perfect place to experience true Puerto Rican culture. Get to know its roots by exploring the vibrant neighborhood of El Viejo San Juan (Old San Juan), which consists mostly of Spanish colonial buildings. Flesh out your self-guided history lesson with a visit to El Castillo San Felipe del Morro, a 16th century citadel that’s a UNESCO World Heritage Site. Then reward yourself with a cooling dip at Luquillo or Carolina Beach, then a tasty tour of the Bacardi rum plant.

Lingering over pain au chocolat in a sidewalk café, relaxing after a day of strolling along the Seine and marveling at icons like the Eiffel Tower and the Arc de Triomphe… the perfect Paris experience combines leisure and liveliness with enough time to savor both an exquisite meal and exhibits at the Louvre. Awaken your spirit at Notre Dame, bargain hunt at the Marché aux Puces de Montreuil or for goodies at the Marché Biologique Raspail, then cap it all off with a risqué show at the Moulin Rouge.

If you’re after a winter sports holiday, you can’t find a more gorgeous place to do it than Interlaken, the popular Swiss resort town. There’s superlative skiing, toboggan rides, miles of sledding tracks (which, like the ski slopes, vary in difficulty), snowboarding… all with amazing views of the mountains. In summer, hike among the ibex at nearby Neiderhorn, or shop for watches in the town’s boutiques.

On the south coast of the Baltic Sea lies Kolobrzeg, a rare combination of beachy atmosphere and medieval architecture. Founded during the Middle Ages, the city survived the Thirty Years’ War and an invasion by Napoleon, but was devastated by WWII. Today, it’s a seaside spa destination that is also popular with outdoor adventurists, particularly for biking the European Route of Brick Gothic. Visit the lighthouse overlooking the River Parseta, stroll the promenade along Kolobrzeg Pier, or visit one of the area’s many wellness centers.

A patchwork of vineyards and olive groves, dotted with whitewashed hill towns and sun-bronzed beaches—Italy’s southern heel has no shortage of photogenic landscapes. There are a few surprises, too, including the baroque city of Lecce and the Itria Valley, with its UNESCO-listed trulli houses.