Get major-city sophistication in a location that is one of the world’s natural wonders. Obviously a hub for those seeking the Rocky Mountain ski slopes, Denver is also home to four major sports teams, major museums and a wide variety of neighborhoods that make the city a destination in its own right.

We've heard Toronto described as "New York City run by the Swiss," and it's true—you can find world-class theater, shopping and restaurants here, but the sidewalks are clean and the people are friendly. The best place to start is literally at the top—the CN Tower, the tallest freestanding structure in the Western Hemisphere.

Hollywood beckons to tourists who long for a brush with Tinseltown glamor. Tour movie studios, slip your hands into the famous prints at the TCL Chinese Theatre, or indulge in a celeb sighting at one of LA’s white-hot nightspots. Spot your favorite star while shopping at The Grove, or forget all about the famous eye candy as you take in the iconic artwork at The Getty Center. For a different type of star-gazing, peek through the telescopes at the Griffith Observatory.

Welcome to bustling San Jose, where Silicon Valley meets Spanish history and modern edifices sit alongside meticulously restored 19th-century buildings. Such is the contrast of this city rich in tradition and, thanks to the tech industry, just plain rich. Five star-hotels and fine restaurants line the streets of the restored downtown area, and the cultural scene is thriving with museums, theater and art to rival any world-class hub. Don't miss the Tech Museum of Innovation, an exploration of Silicon Valley and its impact on the area. History buffs will relish the old mansions and can delve into the city's past at the History Museum of San Jose. Save time for a round of golf or the locals' other favorite pastime, sipping coffee and people-watching at a crowded cafe.

The Pacific Northwest scarcely gets more peaceful than unspoiled Bellingham, a bustling city nestled in the Bellingham Bay. Nature abounds in all directions surrounding this coastal paradise. The waters of the Pacific offer opportunities for whale watching, cruising to Friday Harbor or visiting the Canadian city of Victoria. To the east, Mt. Baker beckons skiers and snowboarders to its slopes. The city itself is alive with vibrant theater, historical museums, gourmet restaurants and fine arts.

Tamarindo is a prime spot for surfing and sportfishing, diving and sunning. Nesting leatherback turtles do their thing along the beaches from October to May and, for some nesting of your own, gorgeous beach houses, B&Bs and luxury hotels line the sunny sands. Shopping and dining options are superb and plentiful, perfect for sampling the true flavors of Costa Rica.

Ten million people call vibrant, passionate, sprawling Bogota home. The energy of this metropolitan heart of Colombia is in part fueled by its hundreds of eclectic and authentic dining hot spots, fantastic wines, and frequent foodie festivals. Ask the locals where they like to eat, then walk off your empanadas and aji with a stroll through the historic district of La Candelaria or during an indulgent shopping adventure on the North Side.

Holland's most modern city began as a fishing village in the 13th century. It was developing into an industrial and trading power when German bombers destroyed the city center and harbor in 1940. However, Rotterdam's unique architecture now brings many visitors to bike around this urbane, cosmopolitan city. Old Dutch-style houses can still be found in historic Delfshaven, from where the pilgrims set sail in 1620. Cultural offerings from summer's carnival to classical music give Amsterdam competition.